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American Journal of PharmTech Research

Mahesh S. Palled

Author Profile
1
Publications
1
Years Active
4
Collaborators
8
Citations

Publications by Mahesh S. Palled

1 publication found • Active 2014-2014

2014

1 publication

Synthesis and Antihypertensive Screening of Novel Substituted 1,2- Pyrazoline Sulfonamide Derivatives

with Avinash M. Bhagwat, Anilchandra R. Bhat, Anand P. Khadke, Anuradha M. Patil
4/1/2014

The novel compounds containing two phenyl rings at 3, 5 position of 1, 2-pyrazoline sulphonamide derivatives synthesized. N-((3-(4-aminophenyl)-5-(3,4-disubstitutedphenyl)-4,5-dihydropyrazol-1-yl)methyl)benzenamine screened  for Angiotensin II receptor antagonistic activity  in  1K-1C goldblatt hypertensive rats using tail cuff method. N-((3-(4-aminophenyl)-5-(3,4-dichlorophenyl)-4,5-dihydropyrazol-1-yl)methyl)benzenamine sulphonamide exhibited potent antihypertensive activity.

Author Statistics
Total Publications:1
Years Active:1
First Publication:2014
Latest Publication:2014
Collaborators:4
Citations:8
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