D. H. Nandal

Pharmacometrics has retained its status in modern pharmacological research. Isolated tissue experiments form an important part of experimental pharmacology. Contractions of isolated tissues are very often recorded by using a recording device and a smoked paper. The key feature of having a good record is to minimize the friction between the smoked paper and the writing point of the recording device. Different types of writing points are in use despite of their disadvantages. We have developed a device to have a writing point from used refill ball point. In our experience, this simple modification improves the recordings of isolated tissue experiments.