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American Journal of PharmTech Research

Published

New Validated HPLC Method for the Estimation of Oxazepam In Pharmaceutical Formulation

Published in February 2017 Issue 1 (Vol. 7, Issue 1, 2017)

New Validated HPLC Method for the Estimation of Oxazepam In Pharmaceutical Formulation - Issue cover

Abstract

A simple, selective, linear, precise and accurate HPLC method was developed and validated for rapid assay of Oxazepam in Bulk and Pharmaceutical tablet Formulation. Isocratic elution at a flow rate of 1.0 ml/min was employed.  The chromatographic analysis was performed on a ODS 5 μm (4.6 mm x 15 cm) or equivalent column at ambient temperature. The mobile phase consisted of Methanol: Water in the ratio of 65:35v/v. The UV detection wavelength was 230nm and 100µl sample was injected. Flow rate was found to be 1.0.  The retention time for Oxazepam was identified. The Average percentage recovery of the method was in the range of 0.5.  The method was validated as per the ICH guidelines. The method was successfully applied for routine quality control analysis of pharmaceutical formulation.

Authors (3)

V.Sreeram

Department of chemistry,(U.G),...

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K.Satyanarayana

Department of chemistry,(U.G),...

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A.V.D.Nagendra kumar

Department of Chemistry, GITAM...

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Article Information

Article ID:
AJPTR71052
Paper ID:
AJPTR-01-001889
Published Date:
2017-02-01

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Downloads:1,060

How to Cite

V.Sreeram & K.Satyanarayana & kumar (2017). New Validated HPLC Method for the Estimation of Oxazepam In Pharmaceutical Formulation. American Journal of PharmTech Research, 7(1), xx-xx. https://ajptr.scholarjms.com/articles/2046

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